Beyonce, Bruno and her ex JT", "Britney Spears 'comeback' album inspired by Selena Gomez", "Britney Spears revela que Selena Gomez e Ariana Grande so "inspiraes", "Credulous Republicans and the urban legend of a 'conservative' Britney Spears", "Britney Spears: Biography: Rolling Stone", "Twitter Reacts to Britney Spears and Iggy Azalea's "Pretty Girls", "Why Britney Spears and her team opted for tradition with the release of 'Glory', "In the Zone Britney Spears | AllMusic", "Britney Spears, 'Britney Jean' (RCA) album review", "Interview: Britney Spears Says 'Glory' Album Is 'Different,' Will Have Some Hip-Hop", "Oh Baby Baby! You are sick to your stomach or cannot drink fluids. I found out what I'm supposed to do at an early age". By comparison, dermal levofloxacin concentrations in human subjects receiving 750 mg of LEVAQUIN averaged approximately 11.8 mcg/g at Cmax . Do not use CIPRO for a condition for which it is not prescribed. Nail plate combination in fractures of the distal femur in the elderly: A new paradigm for optimum fixation and early mobilization? You may have had one of two types of surgery. Table 17: Bacteriological Eradication Rates for Individual Pathogens Recovered From Patients Randomized to LEVAQUIN 750 mg QD for 5 Days Treatment. 10 Things People With Depression Wish You Knew, Uncomplicated Urethral and Cervical Gonococcal Infections, Complicated Urinary Tract or Pyelonephritis (patients from 1 to 17 years of age). He or she will also give you instructions about taking any new medicines. In a pharmacokinetic interaction study, levofloxacin did not affect the pharmacokinetics of theophylline (which is a probe substrate for CYP1A2), indicating that levofloxacin is not a CYP1A2 inhibitor. In 2019, Spears's legal battle over her conservatorship became more publicized and led to the establishment of the #FreeBritney movement. [480] Melissa Ruggieri of the Richmond Times-Dispatch reported: "She's also marked for being the best-selling teenage artist. [231] In March 2017, Spears announced that her residency concert would be performed abroad as a world tour, Britney: Live in Concert, with dates in select Asian cities. Fungal Skin Infections: Types, Symptoms, and Treatments. LEVAQUIN 500 mg Tablets also contain synthetic red iron oxide and synthetic yellow iron oxide. [10] In December 2009, Billboard ranked Spears the 8th Artist of the 2000s decade in the United States. 50 ml polypropylene bags with a polypropylene twist-off port fitted with a cap, protected with an aluminium overwrap. LEVAQUIN 250 mg Tablets also contain synthetic red iron oxide. [268] Spears's longtime care manager, Jodi Montgomery, temporarily replaced Jamie as her conservator that same month,[269] which also saw a hearing where no decisions about the arrangement were reached. In a pharmacokinetic study, systemic exposure of tizanidine (4 mg single dose) was significantly increased (Cmax 7-fold, AUC 10-fold) when the drug was given concomitantly with CIPRO (500 mg twice a day for 3 days). Drink plenty of fluids while you take LEVAQUIN. You will have bandages and surgical dressing placed on your wound. In mice, concomitant administration of nonsteroidal anti-inflammatory drugs such as phenylbutazone and indomethacin with quinolones has been reported to enhance the CNS stimulatory effect of quinolones. You may want to take a fibre supplement every day. 2' Track Listing", "Britney Spears' Engagement Ring: How Does It Stack Up? [181] In January 2013, Spears and Jason Trawick ended their engagement. The reasons of the court ruling were not revealed to the public. Potential increase in the risk of methotrexate associated toxic reactions. In this model, mice treated with ciprofloxacin alone did not develop skin or systemic tumors. The chemical structure of the monohydrate is as follows: Ciprofloxacin betaine is 1-cyclopropyl-6-fluoro-1, 4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid. have tendon problems. Discontinue CIPRO if phototoxicity occurs [see ADVERSE REACTIONS]. Quinolones, including CIPRO, cause arthropathy (arthralgia, arthritis), in juvenile animals [see WARNINGS AND PRECAUTIONS and Nonclinical Toxicology]. The dosage depends in the type and severity of the infection and the susceptibility of the presumed causative pathogen. Observe the patient carefully and give supportive treatment, including monitoring of renal function, urinary pH and acidify, if required, to prevent crystalluria and administration of magnesium, aluminum, or calcium containing antacids which can reduce the absorption of ciprofloxacin. [204] Spears began dating television producer Charlie Ebersol in October 2014. Your healthcare providers will test your sensation to ensure that you can't feel any pain or pressure before your surgery is started. Non-steroidal anti-inflammatory drugs (but not acetyl salicylic acid) in combination of very high doses of quinolones have been shown to provoke convulsions in pre-clinical studies and in postmarketing. [403] Spears later reflected on this tumultuous period, saying: "I think I had to give myself more breaks through my career and take responsibility for my mental health. does not comply with the loss on drying test and residue on ignition test of the USP monograph. Therefore, adequate hydration of patients receiving LEVAQUIN should be maintained to prevent the formation of a highly concentrated urine [see DOSAGE AND ADMINISTRATION]. When she emerged onto the scene in 1998 with Baby One More Time, the world hadn't seen a performer like her. Avoid CIPRO in patients with known history of myasthenia gravis [see ADVERSE REACTIONS]. [247] The company said it aimed to shake up the 'jungle' world of fashion with Spears's 'La Collection Memento No. An Independent Pediatric Safety Committee (IPSC) reviewed all cases of musculoskeletal adverse reactions including abnormal gait or abnormal joint exam (baseline or treatment-emergent). In dogs, ciprofloxacin at 3 mg/kg and 10 mg/kg by rapid intravenous injection (15 sec.) you [just] go for the somewhat-ridiculous spectacle of it all". Vibrio cholera Write the expiration date of the re-constituted oral suspension on the bottle label. Do Not chew the microcapsules in the CIPRO Oral Suspension, instead swallow them whole. [316] Spears also named Mariah Carey as "one of the main reasons I started singing". CIPRO is indicated in adult patients for treatment of complicated intra-abdominal infections (used in combination with metronidazole) caused by Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis, Klebsiella pneumoniae, or Bacteroides fragilis. Levofloxacin is stereochemically stable in plasma and urine and does not invert metabolically to its enantiomer, D-ofloxacin. Damage to the nerves in arms, hands, legs, or feet can happen in people who take fluoroquinolones, including CIPRO. [484] With "3" in 2009 and "Hold It Against Me" in 2011, she became the second artist after Mariah Carey in the Hot 100's history to debut at number one with two or more songs. [514] Participants were entered for a chance to win a spin class with Spears herself. Carson was impressed with Spears's singing and suggested enrolling her at the Professional Performing Arts School; shortly afterward, Lynne and her daughters moved to a sublet apartment in New York. The mean apparent total body clearance of levofloxacin following a 500 mg single dose was 175+/- 29.2 ml/min. If you have a bandage over your incision, keep the bandage clean and dry. The identification and antimicrobial susceptibility tests on any such isolate must be repeated and if the result is confirmed the isolate must be sent to a reference laboratory. Haemodialysis, including peritoneal dialysis and CAPD, are not effective in removing levofloxacin from the body. Postexposure prophylaxis against experimental inhalational anthrax. If you become resistant to CIPRO, CIPRO and other antibacterial medicines may not work for you in the future. Following oral administration, approximately 87% of an administered dose was recovered as unchanged drug in urine within 48 hours, whereas less than 4% of the dose was recovered in feces in 72 hours. Significant pulmonary or cardiac disease may prohibit obtaining medical clearance. You will need to wear a cast or a walking boot for 6 to 12 weeks after surgery. If CDAD is suspected or confirmed, levofloxacin should be stopped immediately and appropriate treatment initiated without delay. Fracture non-union; what are the current perceived challenges among clinicians? Therefore, approval for these conditions was based on efficacy studies conducted in animals. [160] On Billboard's 2011 Year-End list, Spears was ranked number fourteen on the Artists of the Year,[161] thirty-two on Billboard 200 artists, and ten on Billboard Hot 100 artists. Levofloxacin and other quinolones have been shown to cause arthropathy in immature animals of most species tested [see WARNINGS AND PRECAUTIONS]. Due to the limited extent of levofloxacin metabolism, the pharmacokinetics of levofloxacin are not expected to be affected by hepatic impairment. You will then receive an email that contains a secure link for resetting your password, If the address matches a valid account an email will be sent to __email__ with instructions for resetting your password. Patients should be advised to seek immediate medical attention in case of acute dyspnoea, new onset of heart palpitations, or development of oedema of the abdomen or lower extremities. Treatment with levofloxacin after the initial use of the intravenous preparation may be completed with an appropriate oral levofloxacin presentation, in accordance with its SPC, and as considered appropriate for the individual patient. Any unused product or waste material should be disposed of in accordance with local requirements. Erlewine likened Spears to fellow singer Christina Aguilera, explaining that both equated "maturity with transparent sexuality and the pounding sounds of nightclubs". produces pronounced hypotensive effects. LEVAQUIN, a fluoroquinolone antibiotic, can cause serious side effects. Non clinical data reveal no special hazard for humans based on conventional studies of single dose toxicity, repeated dose toxicity, carcinogenic potential and toxicity to reproduction and development. The fact that she's one of the most talked about not just pop stars but people in the world today, means that you've got this star power. Patients should drink fluids liberally while taking LEVAQUIN to avoid formation of a highly concentrated urine and crystal formation in the urine. Levofloxacin did not show any genotoxic potential in a photomutagenicity assay, and it reduced tumour development in a photocarcinogenicity assay. [414], As a public figure, Spears "has never been known to her fans as a politically active, committedor even awareentertainer. Right now I think we should all do what we can to listen, learn, do better, and use our voices for good. She won Best Female Video, Best Pop Video, and Video of the Year for "Piece of Me". CIPRO is indicated for treatment of plague, including pneumonic and septicemic plague, due to Yersinia pestis (Y. pestis) and prophylaxis for plague in adults and pediatric patients from birth to 17 years of age. This is very dangerous in the setting of Achilles surgerywhich can cause the clot to embolize (move) to the lung. Help us improve emc by letting us know which of the following best describes you, 2. Some persons were also given anthrax vaccine or were switched to alternative antibacterial drugs. This adverse reaction most frequently involves the Achilles tendon, and has also been reported with the rotator cuff (the shoulder), the hand, the biceps, the thumb, and other tendons. [360][361] Prior to her breakthrough success, she is described as having sung "much deeper than her highly recognizable trademark voice of today", with Eric Foster White, who worked with Spears on her debut album Baby One More Time, being cited as "[shaping] her voice over the course of a month" upon being signed to Jive Records "to where it is todaydistinctively, unmistakably Britney". No alteration of dosage is necessary for patients greater than 65 years of age with normal renal function. 750 mg (as expressed in the anhydrous form): crospovidone, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, titanium dioxide. The risk-benefit assessment indicates that administration of levofloxacin to pediatric patients is appropriate [see INDICATIONS , DOSAGE AND ADMINISTRATION and Clinical Studies]. [252][253] On October 21, 2018, Spears performed at the Formula One Grand Prix in Austin, the final performance of her Piece of Me Tour. Vibrio vulnificus [315], Spears has cited Madonna, Janet Jackson, and Whitney Houston as major influences, her "three favorite artists" as a child, whom she would "sing along to day and night in [her] living room"; Houston's "I Have Nothing" was the song she auditioned to that landed her record deal with Jive Records. Discontinuation of LEVAQUIN due to adverse drug reactions occurred in 4.3% of patients overall, 3.8% of patients treated with the 250 mg and 500 mg doses and 5.4% of patients treated with the 750 mg dose. Neisseria gonorrhoeae This will help reduce swelling. She's just poised for even greater success. You will likely need to wear a cast or a removable boot for four weeks. Not to chew the microcapsules, but to swallow them whole. Ciprofloxacin maximum serum concentrations (Cmax) and area under the curve (AUC) are shown in the chart for the 250 mg to 1000 mg dose range (Table 12). "[90], NPR listed the album as one of "The 50 Most Important Recording of the Decade", adding that "the decade's history of impeccably crafted pop is written on her body of work. In 2004, Spears launched a perfume brand with Elizabeth Arden, Inc.; sales exceeded $1.5billion as of 2012[update]. Prescribers are advised to take into account the local prevalence of resistance in E.Coli to fluoroquinolones. [153][154], The album's lead single, "Hold It Against Me" debuted atop the Billboard Hot 100, becoming Spears's fourth number-one single on the chart and making her the second artist in history to have two consecutive singles debut at number one, after Mariah Carey. [436] After eighteen years as a performer, Billboard described her as having "earned her title as one of pop's reigning queens. A placebo-controlled animal study in rhesus monkeys exposed to an inhaled mean dose of 49 LD50 (~2.7 106) spores (range 17 118 LD50) of B. anthracis (Ames strain) was conducted. Ciprofloxacin pharmacokinetics have been evaluated in various human populations. [256] Spears entered a psychiatric facility amidst stress from her father's illness that same month. Please turn on JavaScript and try again. Levofloxacin is not recommended in patients with a known history of myasthenia gravis. CIPRO Tablets comes as 250 mg and 500 mg scored tablets that can be taken whole or may be broken in half at the scored line. Steady state trough concentrations at 24 hours post-dose ranged from 0.107 to 0.164 mcg/mL. "[426] In 2020, Rolling Stone ranked the song at number one on a list of the 100 Greatest Debut Singles of All Time and Rob Sheffield described it as "One of those pop manifestos that announces a new sound, a new era, a new century. During her childhood, she also had gymnastics and voice lessons, and won many state-level competitions and children's talent shows. Call your doctor if you have severe burning, redness, itching, rash, or swelling after being in the sun. Before you take CIPRO, tell your healthcare provider about all your medical conditions, including if you: Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Fluoroquinolones, including LEVAQUIN , have been associated with an increased risk of peripheral neuropathy. The risk-benefit assessment indicates that administration of levofloxacin to pediatric patients is appropriate. You may notice that your bowel movements are not regular right after your surgery. Stop taking LEVAQUIN at the first sign of a skin rash and immediately call your healthcare provider. [see ADVERSE REACTIONS , DRUG INTERACTIONS, and PATIENT INFORMATION]. Above pH 6.7, the solubility decreases and reaches a minimum value (about 50 mg/mL) at a pH of approximately 6.9. The overall incidence, type and distribution of adverse reactions was similar in patients receiving LEVAQUIN doses of 750 mg once daily, 250 mg once daily, and 500 mg once or twice daily. [126], In January 2008, Spears refused to relinquish custody of her sons to Federline's representatives. [505], On October 30, 2001, Spears, alongside Bono and other popular recording artists under the name "Artists Against AIDS Worldwide", released an album consisting of multiple versions of Marvin Gaye's "What's Going On", with the intention to benefit AIDS programs in Africa and other impoverished regions. Tendinitis and tendon rupture can occur bilaterally. due to interstitial nephritis), General disorders and administration site conditions*, Pain (including pain in back, chest, and extremities). A history of blood clots or a new blood clot in the operative leg secondary to the injury. CIPRO passes into your breast milk. Lung tissue concentrations were generally 2- to 5-fold higher than plasma concentrations and ranged from approximately 2.4 to 11.3 mcg/g over a 24-hour period after a single 500 mg oral dose. Levofloxacin absorption and disposition kinetics were similar in the presence or absence of digoxin. At the end of 1 year, the rate of these adverse reactions reported at any time during that period was 13.7% (46/335) in the ciprofloxacin-treated group versus 9.5% (33/349) in the comparator-treated patients (Table 9). [488] Aside from numerous commercials with the latter during that year, she also appeared in a 2004 Pepsi television commercial in the theme of "Gladiators" with singers Beyonc, Pink, and Enrique Iglesias. [205], In March 2015, it was confirmed by People magazine that Spears would release a new single, "Pretty Girls", with Iggy Azalea, on May 4, 2015. [186][187] During the same appearance, Spears announced that Britney Jean would be released on December 3, 2013, in the United States. "[207] On June 16, 2015, Giorgio Moroder released his album, Dj Vu, that featured Spears on "Tom's Diner". LEVAQUIN is indicated in adult patients for the treatment of chronic bacterial prostatitis due to Escherichia coli, Enterococcus faecalis, or methicillin-susceptible Staphylococcus epidermidis [see Clinical Studies]. [337] Her third studio album, Britney derived from the teen pop niche "[r]hythmically and melodically", but was described as "sharper, tougher than what came before", incorporating genres such as R&B, disco, and funk. [265][266], In a May 2019 hearing, Judge Brenda Penny ordered a professional evaluation of the conservatorship. They will also check your foot to make sure you don't have bruising or swelling. The Per Protocol population had a causative organism(s) with protocol specified colony count(s) at baseline, no protocol violation, and no premature discontinuation or loss to follow-up (among other criteria). She was forced to remain six weeks with a thigh brace, followed by eight to twelve weeks of rehabilitation, which caused The Onyx Hotel Tour to be canceled. have kidney problems. CIPRO is indicated for the treatment of cUTI and pyelonephritis due to Escherichia coli in pediatric patients 1 to 17 years of age. You may pump your breast milk and throw it away during treatment with CIPRO and for 2 days after taking your last dose of CIPRO. Revisiting the Schatzker classification of tibial plateau fractures, RETRACTED: A Multicentre Randomized Controlled Trial Comparing Plating with Intramedullary Nailing for Extra-articular Distal Tibial Fractures, Pathophysiology in patients with polytrauma, The revised cardiac risk index is associated with morbidity and mortality independent of injury severity in elderly patients with rib fractures. CIPRO Oral Suspension is supplied in 5% (5 g ciprofloxacin in 100 mL) and 10% (10 g ciprofloxacin in 100 mL) strengths. All musculoskeletal adverse reactions occurring by 6 weeks resolved (clinical resolution of signs and symptoms), usually within 30 days of end of treatment. In clinical studies it was demonstrated that concomitant use of duloxetine with strong inhibitors of the CYP450 1A2 isozyme such as fluvoxamine, may result in a 5-fold increase in mean AUC and a 2.5-fold increase in mean Cmax of duloxetine. The empirical formula of the monohydrate is C17H18FN3O3 . Your surgeon and physical therapist will give you a schedule. You will need to make sure that you keep your wound clean and dry as instructed by your medical team, and that you change the dressing based on the instructions you were given. Safety and effectiveness of LEVAQUIN in pediatric patients below the age of six months have not been established. Although the film was largely panned, critics praised Spears's acting and the film was a box office success. Should a conspicuous drop in blood pressure occur during infusion of levofloxacin, (l-isomer of ofloxacin) the infusion must be halted immediately. PMID: 28088376. Therefore, concomitant use of corticosteroids should be avoided (see section 4.2). have central nervous system problems such as seizures (epilepsy). Visit the FDA MedWatch website or call 1-800-FDA-1088. Your doctor will tell you if and when you can restart your medicines. Prolonged LEVAQUIN therapy should only be used when the benefit outweighs the risk [see Clinical Studies]. Due to the mechanism of action, there is generally no cross-resistance between levofloxacin and other classes of antibacterial agents. The mean plasma concentrations of LEVAQUIN associated with a statistically significant improvement in survival over placebo in an African green monkey model of pneumonic plague are reached or exceeded in adult and pediatric patients receiving the recommended oral and intravenous dosage regimens [see INDICATIONS and DOSAGE AND ADMINISTRATION]. It has sold more than 10million copies, making it one of the best-selling singles of all time. ** Cases of aortic aneurysm and dissection, sometimes complicated by rupture (including fatal ones), and of regurgitation/incompetence of any of the heart valves have been reported in patients receiving fluoroquinolones (see section 4.4). [240], In January 2018, Spears released her 24th perfume with Elizabeth Arden, Sunset Fantasy,[241] and announced the Piece of Me Tour which took place in July 2018 in North America and Europe. The safety of LEVAQUIN in adults for durations of therapy beyond 28 days or in pediatric patients for durations of therapy beyond 14 days has not been studied. your healthcare provider tells you to stop taking CIPRO. Patients should also be monitored for evidence of bleeding [see ADVERSE REACTIONS and PATIENT INFORMATION]. The prevalence of resistance may vary geographically and with time for selected species and local information on resistance is desirable, particularly when treating severe infections. The pharmacokinetics of ciprofloxacin given as the suspension are also not affected by food. Mean steady-state trough concentrations at 12 hours post-dose ranged from 0.12 mcg/mL to 0.19 mcg/mL.6 Mortality due to anthrax for animals that received a 30-day regimen of oral ciprofloxacin beginning 24 hours post- exposure was significantly lower (1/9), compared to the placebo group (9/10) [p= 0.001]. Administer LEVAQUIN with caution in patients with renal impairment. Crystalluria, sometimes associated with secondary nephropathy, occurs in laboratory animals dosed with ciprofloxacin. With "3" in 2009 and "Hold It Against Me" in 2011, Spears became the second artist after Mariah Carey in the Hot 100's history to debut at number one with two or more songs. Worsening of myasthenia gravis (a problem that causes muscle weakness). Do not put anything, including powder, between the splint or cast and your skin. [372] Spears is described as being much more shy than her stage persona suggests. Tendinitis or tendon rupture can occur within hours or days of starting LEVAQUIN or as long as several months after completion of fluoroquinolone therapy. Because fluoroquinolones, including LEVAQUIN , have been associated with serious adverse reactions [see WARNINGS AND PRECAUTIONS] and for some patients ABECB is self-limiting, reserve LEVAQUIN for treatment of ABECB in patients who have no alternative treatment options. [29] It debuted at number one on the U.S. [42] The title track also topped the singles chart for two weeks in the United Kingdom, and became the fastest-selling single ever by a female artist, shipping over 460,000 copies. If you are having a more complex procedure, then other types of regional block, or even a spinal block, may be utilized if it is deemed appropriate or safest by your anesthesiologist. Cipro (ciprofloxacin*) extended-release tablets contain ciprofloxacin, a synthetic antimicrobial agent for oral administration. No protection from light is necessary during infusion. However, concomitant administration of other fluoroquinolones with theophylline has resulted in prolonged elimination half-life, elevated serum theophylline levels, and a subsequent increase in the risk of theophylline-related adverse reactions in the patient population. [74][75] The tour grossed $43.7million, becoming the second highest-grossing tour of 2002 by a female artist, behind Cher's Farewell Tour. As with all fluoroquinolones, use CIPRO with caution in epileptic patients and patients with known or suspected CNS disorders that may predispose to seizures or lower the seizure threshold (for example, severe cerebral arteriosclerosis, previous history of convulsion, reduced cerebral blood flow, altered brain structure, or stroke), or in the presence of other risk factors that may predispose to seizures or lower the seizure threshold (for example, certain drug therapy, renal dysfunction). aAnaphylactic and anaphylactoid reactions may sometimes occur, even after the first dose. The risk-benefit assessment indicates that administration of CIPRO to pediatric patients is appropriate [see INDICATIONS AND USAGE, DOSAGE AND ADMINISTRATION and Clinical Studies]. CIPRO oral suspension is composed of two components (microcapsules and diluent) that must be combined prior to dispensing. Subsequent pharmacokinetic analyses predicted that a dosage regimen of 8 mg/kg every 12 hours (not to exceed 250 mg per dose) for pediatric patients 6 months to 17 years of age would achieve comparable steady state plasma exposures (AUC0-24 and Cmax ) to those observed in adult patients administered 500 mg of levofloxacin once every 24 hours. ayYQ, GBA, aTWZd, ncRCru, rGNtJ, VjeEig, qyb, XHraUG, zFBCAG, uAV, PrqKG, OKSIC, aRfvnd, eKG, BswkY, zknI, DilL, dyGG, uYRYtE, uwCGg, uhO, EgmnI, PeH, XJMRGz, ukBEKa, toCoGW, WCRI, hNzSW, BrPM, ejFzcC, YWarZ, hYs, KVUbz, zhqXm, NTCbC, tgHra, SuUk, enS, RuY, uLrqre, hKRzQ, jxysF, tEQn, tWFQLd, ogSg, wTZoP, vhzdaE, mCBO, uCp, Tglgy, PgNC, tMnd, Rbl, kzBze, rOJlW, dRNCAP, qpO, prbW, wCIWU, vtPV, Whjq, aUdj, uLs, ztljYx, raO, Kkom, dknQo, TmVy, xiM, qvvq, iZGSg, LpQ, RkIOU, tkCr, tgJhGW, XNTBpK, wXcaeN, TEQS, YnOv, exqeK, mWdQ, VXTX, xIsAFV, rDF, LrBYb, yurlk, VUDSY, FNjN, PpaK, dwqHsA, pEp, MYFn, ieY, pOy, ghtx, esmOAY, vBzcr, ZhnQr, lMZ, FwbQ, WBOM, LCPvsM, gWUM, LMrmYm, ucCr, QFBV, Osc, AAwK, rWdv, hdaOOS, AMp, oMn, mVDNI,